UTILIZATION OF FRUIT PEEL EXTRACTS OF PERSEA AMERICANA, CYPHOMANDRA BETACEA, MANGIFERA ODORATA AND ARCHIDENDRON PAUCIFLORUM AS ANTIDIABETIC IN EXPERIMENTAL RATS

Research Journal of Pharmaceutical, Biological and Chemical Sciences

Jenny R. Sihombing, Christian Agus Bona Satria Sidabutar, Edy Fachrial, S.Si., M.Si., Almahdy, Zulkarnain Chaidir, Drs. Abdi Dharma, M.Sc, Ph.D

Senin, 11 September 2017 11:12 | Sudah dibaca 894 kali

The present study investigated the antidiabetic activity of four medicinal peel methanolic extract namely Persea americana, Mangifera odorata, Cyphomandra betacea and Archidendron pauciflorum. The experimental rats which administered with alloxan induced diabetic, then treated with peel methanolic extracts of the medicinal plant above. A.pauciflorum peel methanolic extract (AMPE) showed the most significant in decreasing of blood glucose, followed by C.betacea peel methanolic extract (CMPE). The antidiabetic activity of AMPE might be due the antioxidant content which inhibiting the lipid peroxidation and prvent the destruction of pancreatic β cells.

Kata Kunci: Antioxidant, antidiabetic, medicinal plants; alloxan

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